Trying to Avoid Your Sister

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Trying to Avoid Your Sister

Connections between chromosomes are essential for their accurate segregation during cell division. In somatic cells dividing by mitosis, newly replicated sister chromatids are connected by cohesin proteins. When the sister chromatids become attached to microtubules emanating from opposite poles of the spindle, cohesins resist the pulling forces and the ensuing tension stabilizes the chromatid–m...

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ژورنال

عنوان ژورنال: PLoS Biology

سال: 2010

ISSN: 1545-7885

DOI: 10.1371/journal.pbio.1000519